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The research landscape of Alzheimer's disease has changed, the future is at hand. A future when early diagnosis is going to be a routine process. A time when we could know a decade or two in advance if an individual will develop Alzheimer's disease or other forms of dementia. A future when we can immediately and proactively intervene with therapies and other strategies targeting modifiable risk factors. A future when an early diagnosis is not for “giving up” but for “acting o